姓名：姜萌

电子邮箱：30542@hqu.edu.cn

主要研究方向：靶向空间组学技术的开发及应用研究

科研成果：

1. Xia X, Jiang M, Lin C, Ke R. Visualization of Individual RNA Molecules by Proximity Ligation-Based Chromogenic In Situ Hybridization Assay. Methods Mol Biol. 2024;2822:143-156.

2. Jiang M, Wei K, Li M, Lin C,Ke R. Single molecule RNA in situ detection in clinical FFPE tissue sections by vsmCISH. RNA. 2023, 29(6):836-846.

3. Rao X, Zheng L, Wei K, Li M, Jiang M, Qiu J, Zhou Y, Ke R , Lin C. Novel In Situ Hybridization Assay for Chromogenic Single-Molecule Detection of Human Papillomavirus E6/E7 mRNA. Microbiology Spectrum. 2023,  11(2):e0389622.

4. Zhang Q, Xia K, Jiang M, Li Q, Chen W, Han M, Li W, Ke R, Wang F, Zhao Y, Liu Y, Fan C, Gu H. Catalytic DNA-Assisted Mass Production of Arbitrary Single-Stranded DNA. Angew Chem Int Ed Engl. 2023, 62(5): e202212011.

5. Yin J, Lin C, Jiang M, Tang X, Xie D, Chen J, Ke R. CENPL, ISG20L2, LSM4, MRPL3 are four novel hub genes and may serve as diagnostic and prognostic markers in breast cancer. Sci Rep. 2021, 2, 11(1):15610.

6. Lin C, Jiang M, Liu L, Chen X, Zhao Y, Chen L, Hong Y, Wang X, Hong C, Yao X, Ke R. Imaging of individual transcripts by amplification-based single-molecule fluorescence in situ hybridization. New Biotechnology. 2021, 61:116-123.

7. Lin C, Jiang M, Duan S, Qiu J, Hong Y, Wang X, Chen X, Ke R. Visualization of individual microRNA molecules in fixed cells and tissues using target-primed padlock probe assay. Biochem Biophys Res Commun. 2020. 526(3):607-611.

8. Jiang M, Lin C, Ke R. Detection of Individual RNA in Fixed Cells and Tissues by Chromogenic ISH. Bio Protoc. 2020,10(3): e3510.

9. Jiang M, Liu L, Hong C, Chen D, Yao X, Chen X, Lin C, Ke R. Single molecule chromogenic in situ hybridization assay for RNA visualization in fixed cells and tissues. RNA. 2019 25(8):1038-1046.