学位：理学博士学位
学历：博士研究生
职称：教授
所在单位：医学院
学术荣誉：
1、教学工作：先后承担学院5门本科生课程，教学中能够根据教学内容和学生类别，采用灵活多样的教学方式，因此入选“华侨大学2016-2018学年”“学生最喜爱的教师”。
2、学生科创：近三年指导学生获得校级及以上各类科创竞赛或创新项目14项：全国大学生生命科学竞赛一等奖、第11届全国大学生电子商务“创新、创意及创业”挑战赛三等奖、第七届全国青年科普创新实验暨作品大赛（生物环境组）福建赛区一等奖和三等奖各1个、学校第28届“挑战杯”赛特等奖等。
3、科研工作：深入企业需求，主持多项政府和企业课题10余项，经费达到300余万元并注重本科生的科研培养，将科研反哺教学。
4、社会服务：担任学院工会主席；先后担任学院药学系和实验教学中心的主任；担任农工党华大总支主委、泉州市政协委员；同时还兼职多个学术团体的委员、秘书长等。
Liu JQ*, Lian CL, Hu TY, Wang CF, Xu Y, Xiao L, Liu ZQ, Qiu SQ, Cheng BH. Two new farnesyl phenolic compounds with anti-inflammatory activities from Ganoderma duripora，Food Chem. 2018,263:155-162.
发表刊物：Food Chem.
关键字：Anti-inflammation; COX-2; Farnesyl phenol; Ganoderma duripora; MAPK; NF-κB.
摘要：Ganoderma fungi have long been used as a famous traditional medicine and food in country of East Asia. In this work, two new farnesyl phenolic compounds, ganoduriporols A and B (1 and 2), were isolated from the fruiting bodies of Ganoderma duripora, and their structures were elucidated using various spectroscopic methods. Anti-inflammatory activities were assayed and evaluated for the two compounds. Ganoduriporols A and B exhibited dose-dependent anti-inflammatory effects in RAW 264.7 cells. Furthermore, ganoduriporol A was demonstrated to inhibit the production of tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β), interleukin-6 (IL-6) and prostaglandin E2 (PGE2) through the suppression of COX-2, MAPK and NF-κB signaling pathway in LPS-induced macrophage cells. These results suggested that these two new farnesyl phenolic compounds and the fruiting body of G. duripora could serve as anti-inflammatory agents for medicinal use or functional food.
论文类型：基础研究
是否译文：否
发表时间：2018-10-15
上一条： Wang, C.-F., Liu, X.M., Lian, C.L., Ke, J.Y., & Liu, J.Q.*. Triterpenes and Aromatic Meroterpenoids with Antioxidant Activity and Neuroprotective Effects from Ganoderma lucidum. Molecules, 2019, 24(23), 4353.
下一条： Jie-Qing Liu*, Ying Xu, Qin Xiao, Jin-Di Huang, Jun-Jie Ma, Chen-Lei Lian, Mei-Ying Huang, Zhen-bo Du and Cui-Fang Wang*. Dimericursones A and B: two unprecedented hexacyclic dimeric diterpenoids from the root barks of Jatropha curcas. Organic Biomolecular Chemistry. 2018, 16(37): 8305-8310.
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