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    解丽娟

    • 副研究员(自然科学) 硕士生导师
    • 性别:女
    • 学历:博士研究生
    • 学位:工学博士学位
    • 入职时间:2009-05-14
    • 所在单位:医学院
    • 办公地点:德润楼427
    • 电子邮箱:
    • 在职信息:在岗
    • 学科:应用化学
      药物化学
    • 2019当选:泉州市优秀人才

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    个人简介

         解丽娟,华侨大学医学院副研究员,硕士研究生导师。本科毕业于华东理工大学化学制药专业,硕博连读于大连理工大学精细化工国家重点实验室。先后到香港中文大学和美国德州大学奥斯汀分校访学。研究方向:抗肿瘤药物(PARP抑制剂和拓扑异构酶抑制剂)和荧光探针。先后主持国家自然科学基金面上项目、福建省自然基金重点项目、厦门市和泉州市自然科学基金等项目以通讯作者/第一作者在Chemical Communication, Chinese Chemical Letters, Dyes and Pigments Bioorganic & Medicinal Chemistry等期刊发表文章,授权专利10余项。指导的硕士研究生先后获得校级和省级优秀论文。


    教育经历

    [1] 1989.9 -- 1993.7
    华东理工大学       药物化学

    论文成果

  • [1]A Golgi-targetedviscosity rotor for monitoring early Alcohol-Induced Liver Injury.Chemical Communications,2022,58(72):10052-10055.

  • [2]Forthrightly monitoring ferroptosis induced by endoplasmic reticulum stresses through fluorescence lifetimeimaging of microviscosity increases with a specific rotor.Chinese Chemical Letters,2022,33(5):2537–2540.

  • [3]New trends of molecular probes based on thefluorophore 4-amino-1,8- naphthalimide.Chinese Chemical Letters,2019,30(10):1799-1808.

  • [4]Two-photon excitable red fluorophores for imaging living cells.DYES AND PIGMENTS,2018,

  • [5]Direct phosphonation of quinoxalin-2(1H)-ones under transition-metal-free conditions.CHEMICAL COMMUNICATIONS,2016,

  • [6]主动靶向PAMAM给药系统的应用进展.高分子通报,2015,

  • [7]Pseudo-Furocoumarin : Synthesis, DNA-Binding Behavior and Cytotoxicity(类呋喃香豆素的合成与DNA的结合及细胞毒性研究).SPECTROSCOPY AND SPECTRAL ANALYSIS,2014,

  • [8]7-二乙胺基-3-(2'-吡啶) 香豆素的新用途: 溶酶体荧光探针.中国物理学会发光分会;中国科学院长春光学精密机械与物理研究所:发光学报,2012,

  • [9]Fluorescent coumarin derivatives with large stokes shift, dual emission and solid state luminescent properties: An experimental and theoretical study.SCI 二区:DYES AND PIGMENTS,2011,

  • [10]Synthesis of new amonafide analogues via coupling reaction and their cytotoxic evaluation and DNA-binding studies.Bioorganic & Medicinal Chemistry,,2011,

  • [11]5-Non-amino aromatic substituted naphthalimides as potential antitumor agents: Synthesis via Suzuki reaction, antiproliferative activity, and DNA-binding behavior..Bioorganic & Medicinal Chemistry,2011,

  • [12]Novel acenaphtho[1,2-b]pyrrole-carboxylic acid family: Synthesis, cytotoxicity, DNA-binding and cell cycle evaluation..Bioorganic & Medicinal Chemistry,2008,

  • [13]Novel angular furoquinolinones bearing flexible chain as antitumor agent: Design, synthesis, cytotoxic evaluation, and DNA-binding studies..Bioorganic & Medicinal Chemistry,,2008,

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