于厦门大学生物化学与分子生物学专业理学博士学位（师从国家杰青刘刚教授），随后于澳门大学开展联合博士后研究。2026年加入华侨大学材料科学与工程学院。研究方向主要集中在超分子自组装材料的转化医学研究。目前已发表论文七十余篇，其中以第一或通讯作者（含共同）在Adv. Mater等国际期刊上发表论文五十余篇，总影响因子超500，其中IF >10的有15篇（H因子30，总引用超2000次）。相关研究成果获国家专利授权9项，多项专利已完成企业转化，作为技术骨干研发的新型肝癌栓塞剂在四川大学华西医院等十余家三甲医院开展临床试验。研究成果获福建省优秀博士学位论文、福建省医学科技二等奖、厦门市科技进步二等奖、第三届全国博士后创新创业大赛金奖等荣誉奖励。受邀担任Gels期刊（IF: 5.0，中科院二区）客座编辑、Nano-Micro Letters（IF: 36.3，中科院一区Top）、Military Medical Research（IF: 22.9，中科院一区Top）、Chinese Herbal Medicines (IF: 8.9，中科院二区)等期刊青年编委。同时，还受邀担任Cell Biomaterials, Adv. Mater., Adv. Drug Deliver. Rev., Br. J. Pharmacol., Int. J. Surg., Acta Pharm. Sin. B 等百余个SCI期刊审稿人。

代表性论文：

(^#First author, *Corresponding author，最新的影响因子和分区)

1.       Cheng H.^#, Fan X.^#, Ye E., Chen H., Yang J., Ke L., You M., Liu M., Zhang Y., Wu, Y.-L.*, Liu G.*, Loh, X. J.*, and Li, Z*. "Dual Tumor Microenvironment Remodeling by Glucose-contained Radical micelles for MRI Guided Photo-Immunotherapy". Adv. Mater., 2022, 34 (25): 2107674. (IF: 26.8, 中科院1区Top)

2.       Liang X., Liu H., Chen H., Peng X., Li Z., Teng M., Peng Y., Li J., Ding L., Mao j., Chu C., Cheng H.*, Liu G*. "Rhein-based Pickering emulsion for hepatocellular carcinoma: Shaping the metabolic signaling and immunoactivation in transarterial chemoembolization". Aggregate. 2024, 5(4), e552. [封面文章] (IF: 13.7, 中科院1区Top)

3.       Peng Y., Liu H., Liang X., Cao L., Teng M., Chen H., Li Z., Peng X., Mao J., Cheng H.*, Liu G*. "Self-assembling chemodrug fiber-hydrogel for transarterial chemoembolization and radiotherapy-enhanced antitumor immunity". J. Controll. Release, 2025, 380: 1-16. [封面文章] (IF: 11.5,中科院1区Top)

4.       Gao X.^#, Cheng H.^#,*, Teng M., Zhang H., Chen H., Qu S., Liu G*. "Optimizing interventional therapy: A homogeneous lipiodol formulation of Tirapazamine and Sorafenib responsive to post-embolization microenvironment". J. Controll. Release, 2025, 379: 879-889. (IF: 11.5,中科院1区Top).

5.       Chen H., Xiong Y., Teng M., Li Y., Zhang D., Ren Y., Li Z., Liu H., Wen X., Li ZJ., Zhang Y., Rizvi S., Zhuang R., Huang J., Li S.*, Mao J.*, Cheng H.*, Liu G*. "A preclinical and first-in-human study of superstable homogeneous radiolipiodol for revolutionizing interventional diagnosis and treatment of hepatocellular carcinoma". Acta Pharm. Sin. B, 2025, 15(10):5022-5035. (IF: 14.6,中科院1区Top)

6.       Chen K., Lin Z., Chen L., Zhou Y., Zhang W., Wan H., Huo Y., Fu Q., Gao Z., Cheng H.*, Ma X.*, Zhang S*. "TNC-targeted CAR-macrophage therapy alleviates liver fibrosis in mice". Military Med. Res., 2025, 12, 78. https://doi.org/10.1186/s40779-025-00667-3. (IF: 22.9, 中科院1区Top)

7.       Chen H.^#, Teng M.^#, Hu Q.^#, Liang X.^#, Liu H., Li Z., Gao X., Peng Y., Wang X., Syed F., Lv Y., Cheng H.*, Tao R.*, Liu G*. "Carrier-free Methylene Blue Nanomedicine for Prolonged Hepatic Visualization in Anatomical Hepatectomy: A Translational Study from Bench to Bedside". Chem. Eng. J., 2025, 520, 166075. (IF: 13.2,中科院1区Top)

8.       He P., Yi S., Zhang J., Chu C., Peng X., Li C., Sun X., Zhang Y.*, Cheng H.*, Xiong X.*, Liu G*. "Carrier-Free 5-Fu Nanoparticle-Mediated Domestication Therapy for Scar Treatment: A Preclinical and First-in-Human Study". Chem. Eng. J., 2023, 475, 146061. (IF: 13.2,中科院1区Top)

9.       Liang X., Ding L., Ma J., Li J., Cao L., Liu H., Teng M., Li Z., Peng Y., Chen H., Zheng Y., Cheng H.*, Liu G*. "Enhanced Mechanical Strength and Sustained Drug Release in Carrier-Free Silver-coordinated Anthraquinone Natural Antibacterial Anti-inflammatory Hydrogel for Infectious Wound Healing". Adv. Healthc. Mater., 2024, 13, 2400841. (IF: 9.6,中科院2区Top)

10.   Yan Z.^#, Cheng H.^#, Liu Y.^#, Xu W., Cheng Q., Li L., Wu X., Liang Y., Zhao J., Liu G., Li S., Qu S. "Reprogramming Tumor Cell Death via Processing Natural Drug to Carbon Dots Overcomes Collagen Barrier and Activates Antitumor Immunity". Adv. Funct. Mater., 2025, e22706. (IF: 19.0, JCR Q1)

11.   Peng Y.^#, Wu X.^#, Liu H., Yang F., Cheng X., Miao M., Chen S., Yan K., Zheng H.*, Cheng H*, Liu G.*. "Hydrogel- based tumor embolization and synergistic therapeutic strategies". Bioact. Mater., 2025, 59: 17-44. (IF: 20.3,中科院1区Top)

12.   Li C.^#, Cheng H.^#, Zhuang Z.^#, Cao F., Liu H., Zhao L., Rizvia S.F., Wang K., Yang L., Lu X., Zheng Y., Zhang Y., He P., Mao J., Wen X., Zhang L., Jiang L., Lin J., Li D., Chu C., Zeng Y., Lu Z., Liu C., Thompson E.W., Chen Z.*, Wang P.*, Liu G*. "FlexiPlasma Microcatheter–Embolic Material (FPM-EM) Platform: A Non-Inflammatory Pyroptosis Strategy for Precision Hepatocellular Carcinoma Therapy". Small Methods, 2025, e2500231. doi:10.1002/smtd.202500231. (IF: 9.1, 中科院2区)

13.   Cheng, H.^#, Fan, X.^#, Wang, X., Wu, S., Li, Z., Loh, X. J., Wu, Y.-L*. "Hierarchically Self-Assembled Supramolecular Host-Guest Delivery System for Delivery of Chemotherapeutics to Drug Resistant Cancer Tumours". Biomacromolecules. 2018, 19(6): 1926-1938. (IF: 5.4,中科院1区Top)

14.   Chen, H.^#, Cheng, H.^#, Dai, Q.^#, Cheng Y.^#, Zhang, Y., Li, D., Sun Y., Mao, J.*, Ren, K., Chu, C.*, Liu, G*. "A superstable homogeneous lipiodol-ICG formulation for locoregional hepatocellular carcinoma treatment". J. Controll. Release, 2020, 323: 635-643. (IF: 11.5,中科院1区Top)

15.   Fan, X.^#, Cheng, H.^#, Wang, X., Ye, E., Loh, X. J., Wu, Y.-L.*, Li, Z*. "Thermo-responsive Supramolecular Chemotherapy by “V”-shape Armed β-Cyclodextrin Star Polymer to Overcome Drug Resistance". Adv. Healthc. Mater., 2018, 7(7): e1701143. (IF: 9.6,中科院2区Top)

16.   Zhang Y.^#, Cheng H.^#, Chen H.^#, Xu P.^#, Ren E., Jiang Y., Li D., Gao X., Zheng Y., He P., Lin H., Chen B., Lin G., Chen A., Chu C.*, Mao J.*, Liu G.* "A pure nanoICG-based homogeneous lipiodol formulation: Toward precise surgical navigation of primary liver cancer after long-term transcatheter arterial embolization". Eur. J. Nucl. Med. Mol. I., 2022, 49:2605–2617. (IF: 7.6, 中科院1区Top)

17.   Li Z.^#, Cheng H.^#, Wang B., Wu J., Zhang B., Qu S*. "Polylysine-modified near-infrared-emitting carbon dots assemblies: Amplification of tumor accumulation for enhanced tumor photothermal therapy". J. Colloid Interf. Sci., 2024, 668:132-141. (IF: 9.7,中科院1区Top)

18.   Xiong Y.^#, He P.^#, Zhang Y., Chen H., Peng Y., He P., Tian J., Cheng H.*, Liu G.*, Li J*. "Superstable homogeneous lipiodol-ICG formulation: Initial feasibility and first-in-human clinical application for ruptured hepatocellular carcinoma". Regen. Biomater., 2023, 10, rbac106. [封面文章] (IF: 8.1,中科院2区)

19.   Cheng, H., Yang X., Liu G*. "Superstable homogeneous iodinated formulation technology: Revolutionizing transcatheter arterial chemoembolization". Sci. Bull., 2020, 65 (20):1685-1687. (IF: 21.1,中科院1区Top)

20.   Liang X.^#, Cheng H.^#, Liu C., Liu G*. "Antigen self-presenting nanovaccine for cancer immunotherapy". Sci. Bull., 2022, 67 (16): 1611-1613. (IF: 21.1,中科院1区Top)

21.   Teng M., Liang X., Liu H., Li Z., Zhang C., Cheng H.*, Chen H.*, Liu G*. "Cerenkov radiation shining a light for cancer theranostics". Nano Today. 2024, 55, 102174. (IF: 10.9,中科院2区Top)

22.   Chen H., Teng M., Zhang H., Liang X., Cheng H.*, Liu G*. "Advanced radionuclides in diagnosis and therapy for hepatocellular carcinoma". Chinese Chem. Lett., 2022, 33: 3371-3383. (IF: 9.4,中科院1区Top)

23.   Chen, H.^#, Cheng, H.^#, Wu, W.^#, Li, D., Mao, J.*, Chu, C.*, Liu, G*. "The Blooming Intersection of Transcatheter Hepatic Artery Chemoembolization and Nanomedicine". Chinese Chem. Lett., 2020, 31 (6): 1375-1381. (IF: 8.9,中科院1区Top)

24.   Liang X., Huang C., Liu H., Chen H., Shou J., Cheng H.*, Liu G*. "Natural hydrogel dressings in wound care: Design, advances, and perspectives". Chinese Chem. Lett., 2024, 35, 109442. (IF: 8.9,中科院1区Top)

25.   Miao M., Peng Y., Liu H., Chen H., Cheng X., Chen S., Yan K., Cheng H.*, Liu G*. "Micro-nanomaterials-engineered delivery systems for reshaping the tumor immune microenvironment in hepatocellular carcinoma". Chinese Chem. Lett., 2026, 37, 111390. (IF: 8.9,中科院1区Top)

26.   Cheng, H., Wu, Z., Wu, C., Wang X., Liow, S, S., Wu, S., Li, Z., Wu, Y.-L*. "Overcoming STC2 mediated drug resistance through drug and gene codelivery by PHB-PDMAEMA cationic polyester in liver cancer cells". Mat. Sci. Eng. C-Mater., 2018, 83: 210-217. (IF: 8.1,中科院2区Top)

27.   Peng Y., Liu H., Miao M., Cheng X., Chen S., Yan K., Mu J.*, Cheng H.*, Liu G*. "Micro-Nano Convergence-Driven Radiotheranostic Revolution in Hepatocellular Carcinoma". ACS Appl. Mater. Interfaces, 2025, 17, 29047−29081. (IF: 8.2,中科院2区)

28.   Cai J., Zhong M., Xu J., Cheng H.*, Xu S*. "Codelivery of Triptolide and IFN-γ to boost antitumor immunity for triple-negative breast cancer". Int. Immunopharmacol., 2023, 120:110346. (IF: 4.7,中科院2区)

29.   Xu S., Cai J., Cheng H.*, Wang W*. "Sustained release of therapeutic gene by injectable hydrogel for hepatocellular carcinoma". International Journal of Pharmaceutics: X, 2023, 6, 100195. (IF: 6.4,中科院2区)

30.   Fan, X.^#, Ke, L.^#, Cheng, H.^#, Chen, H., Li, Z-G., Ye, E., Loh, X. J., Wu, Y.-L.*, Liu, G.*, Li, Z*. "Enhanced drug retention by anthracene crosslinked nanocomposites for bimodal imaging-guided phototherapy". Nanoscale, 2021, 13, 14713-14722. (IF: 5.1,中科院3区)

31.   Cheng, H.^#, Fan, X.^#, Wu, C., Wang, X., Wang, L.-J., Loh, X. J., Li, Z.*, Wu, Y.-L*. "Cyclodextrin-Based Star-Like Amphiphilic Cationic Polymer as a Potential Pharmaceutical Carrier in Macrophages". Macromol. Rapid Comm., 2018, 40(5): e1800207. (IF: 4.3,中科院3区)

32.   Li Z.^#, Cheng H.^#, Mao J.*, Liu G*. "Conversion Therapy of Intermediate and Advanced Hepatocellular Carcinoma with Superstable Homogeneous Iodinated Formulation Technology". Sci. China Life Sci., 2022, 65, 2114-2117. (IF: 9.5,中科院1区Top)

33.   Zhou Y., Chen K., Cheng H.*, Zhang S*. "Recent advances in polysaccharide-based hydrogels for tumor immunotherapy". Gels, 2025, 11(3):152. (IF: 5.3,中科院2区)

34.   Fan, X.^#, Cheng, H.^#, Wu, Y., Loh, X. J., Wu, Y.-L.*, Li, Z*. "Incorporation of Polycaprolactone to Cyclodextrin-based Nanocarrier for Potent Gene Delivery". Macromol. Mater. Eng., 2018, 303: e1800255. (IF: 4.6,中科院3区)

35.   Chan, B. Q. Y.^#, Cheng, H.^#, Liow, S, S., Dou, Q., Wu, Y.-L.*, Li, Z.*, Loh, X. J*. "Poly (carbonate urethane)-based thermogels with enhanced drug release efficacy for chemotherapeutic applications". Polymers, 2018, 10(1): 89. (IF: 4.9,中科院3区)

36.   Ke, L.^#, Li, Z-G.^#, Fan, X., Loh, X.J., Cheng, H.*, Wu, Y-L.*, and Li, Z*. "Cyclodextrin-based hybrid polymeric complex to overcome dual drug resistance mechanisms for cancer therapy". Polymers, 2021, 13(8):1254. (IF: 4.9,中科院3区)

37.   Cheng, H., Tai. H. C*. "A nanovesicle platform to deliver neoantigens and immune checkpoint inhibitors: to ASPIRE for novel cancer vaccines". MedComm-Biomaterials and Applications, 2022, 1: e4. DOI: 10.1002/mba2.4

38.   Cao, L.^#, Zhu, Y.^#, Wang, W., Wang, G.*, Zhang, S.*, Cheng, H*. "Emerging Nano-based Strategies against Drug Resistance in Tumor Chemotherapy". Front. Bioeng. Biotech., 2021, 9: 798882. (IF: 4.8,中科院3区)

39.   Liu H.^#, Liang X.^#, Teng M.^#, Li Z., Peng Y., Wang P., Chen H.*, Cheng H.*, Liu G*. "Cold atmospheric plasma: an emerging immunomodulatory therapy". Adv. Therapeutics, 2024, 7, 2300399. (IF: 2.6,中科院4区)

40.   Peng Y., He P., Gao X., Liu G*, Cheng H*. "A superstable homogeneous lipiodol-nanoformulation to overcome the dilemma of interventional embolization chemotherapy" Front. Bioeng. Biotech., 2022, 10:952194. (IF: 4.8,中科院3区)

41.   Li, Z-G.^#, Cheng, H.^#, Ke, L-J., Liu, M., Wang, C., Loh, X. J., Wu. Y.-L.*, Li, Z.* "Recent Advances in New Copolymer Hydrogel-Formed Contact Lenses for Ophthalmic Drug Delivery". ChemNanoMat, 2021, 6(5): 564-579. (IF: 2.6,中科院4区)

42.   Zeng W.^#, Zhang, C.^#, Cheng, H.^#, Wu, Y.-L., Liu, J., Chen, Z., Huang, J. G., Ericksen, R. E., Chen, L., Zhang, H., Wong, A. S., Zhang, X.-K., Han, W., Zeng, J.-Z*. "Targeting to the Non-genomic Activity of Retinoic Acid Receptor-Gamma by Acacetin in Hepatocellular Carcinoma". Sci. Rep., 2017, 7(1): 348. (IF: 3.9,中科院3区)

43.   Wu Z.^#, Cheng H.^#, Liu J.^#, Zhang S., Zhang M., Liu F., Li Y., Huang Q., Jiang Y., Chen S., Lv L., Li D.*, Zeng JZ*. "The oncogenic and diagnostic potential of stanniocalcin 2 in hepatocellular carcinoma". J. Hepatocell. Carcino., 2022, 9:141-155. (IF: 3.4,中科院3区)

44.   Peng Y.^#, Cheng H.^#, Liu H., Zhang Y., Liu G*. "Super-stable homogeneous embolic agents for transformation treatment of hepatocellular carcinoma". iRADIOLOGY, 2023, 1:190-194.

45.   Liu H., Liang X., Peng Y., Liu G.*, Cheng H*. "Supercritical fluids: an innovative strategy for drug development". Bioengineering, 2024, 11(8), 788. (IF: 3.7,中科院3区)

46.   Huang, S., Cao, L., Cheng, H.*, Li, D., Li, Y, Wu, Z*. "The Blooming Intersection of Subfatin and Metabolic Syndrome". Rev. Cardiovasc. Med., 2021, 22(3): 799-805. (IF: 1.3,中科院3区)

47.   Cao, L., Zhu, Y., Wu, Z., Wang, G., Cheng, H*. "Engineering nanotheranostic strategies for liver cancer".  World J. Gastro. Oncol.,2021, 13(10): 1213-1228. (IF: 2.5,中科院4区)

48.   Cai J., Cheng H.*, Xu S*. "ABHD5 as a friend or an enemy in cancer biology?". Front. Oncol., 2024, 14:1447509. (IF: 3.3,中科院3区)

49.   Cai J., Cheng H.*, Xu S*. " Liver cancer burden attributable to high body mass index and high fasting plasma glucose in BRICS countries (1990–2021): a Global Burden of Disease 2021analysis with projections to 2050". Front. Oncol., 2025, 15:1627282. (IF: 3.3,中科院3区)

50.   Cheng Q.^#, Wang Q.^#, Cheng H.^#, Wang H., Qu. S. "Metal-FreeCarbonDots as Photon-Triggered Pyroptosis Inducers for EnhancedCancer Immunotherapy". Chem. Eur. J., 2025, e02351. https://doi.org/10.1002/chem.202502351. (IF: 3.7,中科院3区)

51.   Zhou Y., Chen K., Zhang Y., Cheng H.*, Zhang S*. "Adoptive cell therapy for HBV-associated liver diseases", Biomedical Technology, 2025, 12, 100116.

52.   Cao L., Chen Y., Xu S.*, Cheng H*. "Is NAD(P)H quinone oxidoreductase 1 a tumor promoter or suppressor in gastric cancer?". Front. Oncol., 2023, 13:1143108. (IF: 3.3,中科院3区)

获奖及荣誉：

1.         2023年福建省优秀博士学位论文，论文题目：基于药物高效递送的多功能光诊疗剂构建及其在肝癌联合治疗中的应用研究

2.         项目名称：“基于功能化影像探针的肿瘤诊疗新技术及应用”，厦门市科学技术进步奖二等奖，主要完成人。获奖人：刘刚、张现忠、楚成超、程红伟、王骁勇、尹震宇、李文岗、潘金韬。

3.         项目名称：“肿瘤诊疗一体化分子影像探针设计、构建及临床应用研究”，福建省医学科技奖二等奖，主要完成人。获奖人：刘刚、张现忠、楚成超、程红伟、毛景松、王骁勇、尹震宇。

4.         中华医学会第二十六次全国放射学学术大会，口头报告，最佳论文奖，报告题目：Superstable Homogeneous System of Drug-Iodine Oil and Its Application in Transarterial Embolization and Fluorescence Surgery of Hepatocellular Carcinoma。

5.         中国毒理学会2023纳米毒理学分会，口头报告，Nanoscale & Nanoscale Advances优秀论文奖。报告题目：可视化的TEMPO基聚合物在肝癌诊疗中的研究。

6.         美国化学会ACS 2023春季年会亚太胶体和界面化学分会场，口头报告， 获Rising Talents Prize。

7.         中国国际大学生创新大赛（2023）高教主赛道，铜奖，指导教师：刘刚、楚成超、程红伟、张阳、蒲晓业、游璐茜、陈川

8.         第九届福建省“互联网+”大学生创新创业大赛（高教主赛道），金奖，指导老师：刘刚、楚成超、程红伟、张阳、陈川

9.         2024年第一季度“Wiley威立中国开放科学高贡献作者-Outstanding contribution in Open Science”.