Journal:RSC Advances
Place of Publication:ROYAL SOC CHEMISTRY
Abstract:Ir-catalysed direct sulfamidation of quinazolinones has been achieved. A series of ortho-diamided quinazolinones were obtained in up to 96% yields. This transformation could proceed smoothly with a low catalyst loading under mild conditions with nitrogen released as the sole byproduct. This approach potentially provides an environmentally benign sulfamidation process for atom/step economic syntheses of useful pharmaceutical molecules or important building blocks
Volume:8
Page Number:8450-8454
Number of Words:6000
Translation or Not:no
Date of Publication:2017-12-04
First Author:CXL,WLH