Jie-Qing Liu*, Ying Xu, Qin Xiao, Jin-Di Huang, Jun-Jie Ma, Chen-Lei Lian, Mei-Ying Huang, Zhen-bo Du and Cui-Fang Wang*. Dimericursones A and B: two unprecedented hexacyclic dimeric diterpenoids from the root barks of Jatropha curcas. Organic Biomolecular Chemistry. 2018, 16(37): 8305-8310.
Journal:Organic Biomolecular Chemistry.
Abstract:Dimericursones A and B (1 and 2), two unprecedented hexacyclic dimeric diterpenoids, were obtained from the root barks of Jatropha curcas. Their structures were elucidated by extensive spectroscopic analysis, electronic circular dichroism calculations, and single-crystal X-ray diffraction. Dimericursone B (2) showed significant inhibition on nitric oxide production of lipopolysaccharide-induced RAW264.7 macrophages with IC50 values of 5.65 μM.
Indexed by:Unit Twenty Basic Research
Translation or Not:no
Date of Publication:2018-09-26
Pre One:Liu JQ*, Lian CL, Hu TY, Wang CF, Xu Y, Xiao L, Liu ZQ, Qiu SQ, Cheng BH. Two new farnesyl phenolic compounds with anti-inflammatory activities from Ganoderma duripora，Food Chem. 2018,263:155-162.
Next One:Xiao, Q.; Wang, C.-F.; Chen, J.; Lian, C.-L.; Xu, Y.; Xiao, L.; Liu, J.-Q.*, Three new withanolides from the calyces of Nicandra physaloides. Steroids 2018, 131, 32-36.
