Journal:Steroids
Key Words:Nicandra physaloides; Nicphysatones A-C; Solanaceae; Steroids; Withanolides.
Abstract:Chemical investigation on ethyl acetate extract of the calyces of Nicandra physaloides resulted in the isolation of three new withanolides named as nicphysatone A (1), nicphysatone B (2), nicphysatone C (3), together with five known withanolides, nic 17 (4), nic 7 (5), nic 2 (6), withahisolide G (7) and nicaphysalin B (8). The structures were determined by comprehensive spectroscopic experiments. The discovery enriched the diversity of natural withanolides and could serve as scaffolds for the synthesis of more potent modified withanolides.
Indexed by:Unit Twenty Basic Research
Translation or Not:no
Date of Publication:2018-05-13