个人简介：副教授、硕士生导师。2023年入选福建省高层次人才C类和泉州市高层次人才(第三层次)。先后主持国家自然科学基金青年项目、泉州市科技计划项目以及华侨大学人才项目。迄今为止发表SCI收录论文26篇，论文他人引用次数300余次。获得中国发明专利授权4项。研究兴趣包括：双重发射金属配合物的构建及其对生物大分子的检测；发光功能配合物的设计合成及其OLEDs应用。

主讲课程：无机化学(本科生)、配位化学(研究生)

招生信息：每年可招收1-2名化学或药学背景的硕士研究生

教育背景：

1. 2010年9月—2015年7月, 中国科学院化学研究所（硕博连读）, 有机化学，理学博士

2. 2006年9月—2010年7月, 湘潭大学, 应用化学，理学学士

3. 2013年11月—2014年3月, 法国雷恩第一大学, 化学学院，访问学者

  科研项目：

1. 国家自然科学青年基金，22004041，基于双重发射金属钌配合物的蛋白纤维化检测，2021/01 - 2023/12，24万元，结题，主持

2. 泉州市科技计划项目，2019C064R，金属配合物蓝光材料的设计合成及其在有机发光二极管中的应用，2019/09 - 2022/08，30万元，结题，主持

3. 华侨大学科研启动基金，600005-Z16X0045，基于二茂铁多中心混合价体系的研究，2016/05 - 2019/05，4万元，结题，主持

4. 国家自然科学青年基金，81602970，新型小分子procaspase3变构激活剂的分子构建和抗肿瘤活性评价，2016/10 - 2019/10，17.3万元，结题，参与

  通讯或第一作者论文：

16. Si-Hai Wu*, Jian-Cheng Chen, Zhe Zhang, Ren-Hui Zheng, Hui-E. Peng, Zifeng Zhao, Dian-Xue Ma, Zhong-Qiu Li, Jiang-Yang Shao*, Yu-Wu Zhong*. High-Performance Solution-Processed OLEDs Utilizing a Nonplanar Terdentate Chloroplatinum Emitter. Sci. China Chem. 2025, 68, 4150–4159. (IF = 10.4, 中科院1区, Top期刊)

15. Tonglv Pu, Si-Hai Wu, Liuyan Cai, Wenjia Pu, Yilong Yuan, Zhenjing Zhuang, Shumin Yang, and Lianhui Wang*. Regio- and Stereoselective β‑Sulfonylamination of Alkynes via Photosensitized Bifunctional N−S Bond Homolysis. Org. Lett. 2024, 26, 10604–10610. (IF = 4.9, 中科院1区)

14. Si-Hai Wu,*^,# Junjie Ma,^# Hui-E. Peng, Ren-Hui Zheng, Zhe Zhang, Rong Yang, Lianhui Wang, Jieqing Liu, Jiao Mu, Meirong Liu, Zhong-Qiu Li, Zhong-Liang Gong, Jiang-Yang Shao,* and Yu-Wu Zhong*. Ratiometric Imaging Detection of Amyloid‑β Fibrils by a DualEmissive Tris-Heteroleptic Ruthenium Complex. Inorg. Chem. 2024, 63, 17983–17992. (IF = 4.3, 中科院2区, Top期刊)

13. Chao Gong, Jialun Huang, Liuyan Cai, Yilong Yuan, Tonglv Pu, Mingjie Huang, Si-Hai Wu*, and Lianhui Wang*. Visible-Light-Promoted Thiolation of Benzyl Chlorides with Thiosulfonates via a Photoactive Electron Donor−Acceptor Complex. J. Org. Chem. 2024, 89, 9450−9461. (IF = 3.3, 中科院2区)

12. Si-Hai Wu*, Zhe Zhang, Ren-Hui Zheng, Rong Yang, Lianhui Wang*, Jiang-Yang Shao, Zhong-Liang Gong* and Yu-Wu Zhong. Dual-Emissive Monoruthenium Complexes of N(CH₃)-Bridged Ligand: Synthesis, Characterization, and Substituent Effect. Materials 2023, 16, 6792. (Invited Paper, IF = 3.1, 中科院3区)

11. Hailong Wang, Haichao Huang, Chao Gong, Yong Diao, Jianmei Chen, Si-Hai Wu*, and Lianhui Wang*. Nickel-Catalyzed Chemo- and Regioselective Benzylarylation of Unactivated Alkenes with o-Bromobenzyl Chlorides. Org. Lett. 2022, 24, 328–333. (IF = 4.9, 中科院1区)

10. Haichao Huang, Hailong Wang, Chao Gong, Zhenjing Zhuang, Wenmin Feng, Si-Hai Wu* and Lianhui Wang*. Synthesis of 2-trifluoromethylquinolines through rhodiumcatalysed redox-neutral [3+3] annulation between anilines and CF3-ynones using traceless directing group. Org. Chem. Front. 2022, 9, 413–419. (IF = 4.6, 中科院1区)

9. Yu Wang, Kun Huang, Yali Gao, Dandan Yuan, Lin Ling, Jieqing Liu, Si-Hai Wu, Roufen Chen, He Li, Yizu Xiong, Han Liu, Junjie Ma*. Discovery of quinazoline derivatives as novel small-molecule inhibitors targeting the programmed cell death-1/programmed cell death-ligand 1 (PD-1/PD-L1) interaction. Eur. J. Med. Chem. 2022, 229, 113998. (IF = 6.0, 中科院2区)

8. Si-Hai Wu*, Rong Yang, Bin Sun, Jian-Hong Tang, Zhong-Liang Gong, Junjie Ma, Lianhui Wang, Jieqing Liu, Dian-Xue Ma, Jiang-Yang Shao*, Yu-Wu Zhong*. Dual-Emissive Tris-Heteroleptic Ruthenium Complexes: Tuning the DNA-Triggered Ratiometric Emission Response by Ancillary Ligands. Inorg. Chem. 2021, 60, 14810–14819. (IF = 4.3, 中科院2区, Top期刊)

7. Si-Hai Wu*, Dian-Xue Ma, Zhong-Liang Gong, Junjie Ma, Rong Yang, Jiang-Yang Shao*, Yu-Wu Zhong*. Synthesis, Photophysical, and Computational Studies of a Bridged IrIII-PtII Heterodimetallic Complex. Crystals 2021, 11, 236. (Invited Paper, IF = 2.4, 中科院4区)

6. Si-Hai Wu*, Jiang-Yang Shao, Zifeng Zhao, Junjie Ma, Rong Yang, Na Chen, Jian-Hong Tang*, Zuqiang Bian, Yu-Wu Zhong*. Ligand Engineering toward Deep Blue Emission in Nonplanar Terdentate Platinum(II) Complexes. Organometallics 2021, 40, 156–165. (IF = 2.5, 中科院3区)

5. Jiang-Yang Shao, Si-Hai Wu*, Junjie Ma, Zhong-Liang Gong, Tian-Ge Sun, Yulong Jin, Rong Yang, Bin Sun, Yu-Wu Zhong*. Ratiometric detection of amyloid-β aggregation by a dual-emissive tris-heteroleptic ruthenium complex. Chem. Commun. 2020, 56, 2087–2090. (Front Cover, IF = 4.3, 中科院2区)

4. Si-Hai Wu*, Zhong-Liang Gong, Jiang-Yang Shao, Rong Yang, Yu-Wu Zhong*. Dual-emissive transition-metal complexes and their applications as ratiometric photoluminescent probes. Sci. Sin. Chim. 2020, 50, 315–323. (Invited Review, 特刊)

3. Zhi-Juan Li, Jiang-Yang Shao, Si-Hai Wu*, Yu-Wu Zhong*. Nanocrystalline Sb-doped SnO2 films modified with cyclometalated ruthenium complexes for two-step electrochromism. Dalton Trans. 2019, 48, 2197–2205. (IF = 3.5, 中科院3区)

2. Si-Hai Wu*, Jiang-Yang Shao, Zhong-Liang Gong, Na Chen, Yu-Wu Zhong*. Tuning the dual emissions of a monoruthenium complex with a dangling coordination site by solvents, O₂, and metal ions. Dalton Trans. 2018, 47, 292–297. (IF = 3.5, 中科院3区)

1. Si-Hai Wu*, Jiang-Yang Shao, Xiaojuan Dai, Xiuling Cui, Yu-Wu Zhong*. Synthesis and Characterization of Trisbidentate Ruthenium Complexes of Di(pyrid-2-yl)-methylamine. Eur. J. Inorg. Chem. 2017, 2017, 3064–3071. (IF = 2.2, 中科院4区)

2016年以前：

1. Yu-Wu Zhong*, Si-Hai Wu, Stephen E. Burkhardt, Chang-Jiang Yao, Héctor D. Abruña*. Mononuclear and Dinuclear Ruthenium Complexes of 2,3-Di-2-pyridyl-5,6-diphenylpyrazine: Synthesis and Spectroscopic and Electrochemical Studies. Inorg. Chem. 2011, 50, 517–524. (SCI二区)

2. Si-Hai Wu, Stephen E. Burkhardt, Jiannian Yao, Yu-Wu Zhong*, Héctor D. Abruña*. Near-Infrared Absorbing and Emitting RuII−PtII Heterodimetallic Complexes of Dpdpz (Dpdpz = 2,3-Di(2-pyridyl)-5,6-diphenylpyrazine). Inorg. Chem. 2011, 50, 3959–3969. (SCI二区)

3. Si-Hai Wu, Héctor D. Abruña, and Yu-Wu Zhong*. Rhenium Complexes of 2,3-Di(2-pyridyl)-5,6-diphenylpyrazine: Synthesis, Characterization, and Reactivity. Organometallics 2012, 31, 1161–1167. (SCI二区)

4. Si-Hai Wu, Stephen E. Burkhardt, Yu-Wu Zhong*, Héctor D. Abruña*.  Cyclometalated Ruthenium Oligomers with 2,3-Di(2-pyridyl)-5,6-diphenylpyrazine: A Combined Experimental, Computational, and Comparison Study with Noncyclometalated Analogous. Inorg. Chem. 2012, 51, 13312–13320. (SCI二区)

5. Si-Hai Wu, Jun-Jian Shen, Jiannian Yao, Yu-Wu Zhong*. Asymmetric Mixed-Valence Complexes that Consist of Cyclometalated Ruthenium and Ferrocene: Synthesis, Characterization, and Electronic Coupling Studies. Chem. Asian J. 2013, 8, 138–147. (SCI二区)

6. You-Ming Zhang^〃, Si-Hai Wu^〃, Chang-Jiang Yao , Hai-Jing Nie , Yu-Wu Zhong*. A Bis(terpyridine)ruthenium Complex with Three Redox-Active Amine Sites: Electrochemical, Optical, and Computational Studies. Inorg. Chem. 2012, 51, 11387–11395. (SCI二区, 共同一作)

7. Si-Hai Wu, Yu-Wu Zhong*, Jiannian Yao. 2,3-Di(2-pyridyl)-5-phenylpyrazine: A NN-CNN-Type Bridging Ligand for Dinuclear Transition-Metal Complexes. Chem. Asian J. 2013, 8, 1504–1513. (SCI二区)

8. Si-Hai Wu, Jiang-Yang Shao, Hong-Wei Kang, Jiannian Yao, Yu-Wu Zhong*. Substituent and Solvent Effects on the Electrochemical Properties and Intervalence Transfer in Asymmetric Mixed-Valent Complexes Consisting of Cyclometalated Ruthenium and Ferrocene. Chem. Asian J. 2013, 8, 2843–2850. (SCI二区)

  授权专利：

1.吴四海、刘接卿、马俊杰，一种有机蓝色发光材料及其制备方法，2020-08-07，中国，ZL201711093178.5

2. 吴四海，一种金属钌配合物比率发光探针及其制备和利用该发光探针检测淀粉样蛋白纤维化过程的应用，2022-10-14，中国，ZL201911068985.0

3. 吴四海，一种铂配合物蓝光材料及其制备和应用，2023-07-18，中国，ZL202011110875.9

4. 吴四海、张哲，一种发光材料及其制备方法和应用，2025-08-19，中国，ZL202311192919.0