Qr code
中文
Miao Nan

Associate professor

Supervisor of Master's Candidates


Gender:Female

Date of Birth:1988-11-07

Education Level:博士研究生

School/Department:华侨大学医学院

Business Address:华侨大学厦门校区泛华科技大楼B201

E-Mail:

Status:在岗

Other Post:药理学教研室主任

Discipline:Biomedical Engineering
Biomedical Engineering

Honors and Titles:

2024-07-25   全国大学生基础医学实验设计创新大赛(西部、中南部赛区) 三等奖 (指导老师)

2024-05-07   华侨大学第四届基础医学创新研究暨实验设计大赛 三等奖(指导老师)

2023-12-29   Brain Sciences 2023 Outstanding Reviewer Award

2024-04-14   医学院“精彩一堂课”三等奖

2023-06-30   2022-2023年 考核优秀

2019-06-30   2018-2019年 考核优秀

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Profile

       苗楠,副教授,硕士生导师,2016年6月获得博士学位,同年9月入职华侨大学医学院,加入孙涛课题组(精准医疗研究中心,现有1名教授,2名副教授) 近五年来以第一,通讯,以及参与作者身份,华侨大学一单位发表一区、二区SCI论文20多篇。主持国家自然科学基金青年项目1项、福建省自然科学基金面上项目2项、厦门市自然科学基金青年项目1项等,总到账经费110万元。申请专利4项,授权国际专利2项,排名第一。

       现承担药学、临床医学专业本科生《疾病动物模型》、《医学遗传学》等4-5门中英文课程。担任5名本科生的成长导师,其中指导学生团队获国家基础医学实验技能大赛西南赛区三等奖。指导本科生毕业设计10余名,5名优秀毕业论文。参编《生物医学实验指导》等教科书。 获得2018-2019, 2022-2023和2024-2025考核优秀,获得医学院精彩一堂课三等奖

      已培养研究生9名,在读4名,多名学生获得一等奖学金、二等奖学金、优秀毕业论文和校级优秀学生。

      研究方向:[1]非编码RNAlncRNA以及微小(miRNA、siRNA、piRNA等)在人类神经元发育,及在焦虑、抑郁等相关疾病的机制研究; [2] 小鼠大脑发育与神经生物学;  [3]表观遗传学(DNA甲基化、染色体开放)在人的染色体疾病中的机制研究。地址: 福建省厦门市华侨大学厦门校区泛华科技大楼B201室   邮编361021

      

★2026招生计划:学术硕士1名与专业硕士1名( 欢迎感兴趣的同学邮件咨询:miaonan@hqu.edu.cn,欢迎有理想、敢拼搏的你加入我们)★


1. 科研项目(主持,总到账经费110W

1.国家自然科学青年基金,2022/1-2024/12,30W (结题)

2.福建省自然科学基金面上项目,2025/9-2028/8,10W (在研)

3.厦门市自然科学基金青年项目,2025/7-2028/6,5W(在研)

4.福建省自然科学基金面上项目,2019/5-2022/6,4W(结题)

3.华侨大学中青年教师科技创新资助计划,2022/5-2026/5,40W (在研)

4.华侨大学高层次人才科研启动费项目12W (在研)

5.华侨大学启动经费4W(在研)

6.中国博士后基金二等资助5W(结题)


2. 研究生培养

2022级 潘   贤(生物医学工程,一等奖学金,优秀毕业论文,就职于大博医疗

2023级 李思琪(药   学,二等奖学金 2次) 王珍珍(生物与医药,一、二等奖学金,校级优秀学生)

2024级 付雨晗(生物与医药)

2025级 张   妍(药          学)


3. 科研情况(详细信息见:https://www.webofscience.com/wos/author/record/AGY-9361-2022

(1)第一、通讯作者

  1. Siqi Li , Yuhan Fu , Zhenzhen Wang, Yan Zhang , Tao Sun and Nan Miao (#)  (2026) .The Regulatory potential of Long Non-Coding RNA in Bipolar Disorder. International Journal of Molecular Sciences (Accept)

  2. Nan Miao, Trevor Lee, Liying Chen, Hegan Zhang, Jing Wang, Julianne Sun, Jason Sun, Yongqiang Sha, Shi-Ying Huang and Tao Sun  (#) (2026). Molecular signatures of cell diversity modulated by lncRNAs in the human fetal spinal cord. IScience.2026.May DOI: 10.1016/j.isci.2026.115399.

  3. Pan X, Dai W, Wang Z, Li S, Sun T, Miao Nan(#) (2024). PIWI-Interacting RNAs: A Pivotal Regulator in Neurological Development and Disease. Genes (Basel). 2024 May 21;15(6):653. doi: 10.3390/genes15060653. PMID: 38927589; 

  4. Nan MiaoZhiwei Zeng, Trevor Lee, Qiwei Guo, Wenwei Zheng, Wenjie Cai, Wanhua Chen, Jing Wang and Tao Sun (#) (2023). Integrative epigenome profiling of 47XXY provides insights into whole genomic DNA hypermethylation and active chromatin accessibility. Frontiers in Molecular Bioscience.2023,Mar 27;10:1128739. doi: 10.3389/fmolb.2023.1128739 

  5.  Wenhua Li, Shanshan Guo, Nan Miao (#)(2022). Transcriptional responses of fluxapyroxad-induced dysfunctional heart in zebrafish (Danio rerio) embryos. Environmental Science and Pollution Research. 2022 Jul 21. doi: 10.1007/s11356-022-21981-6. 

  6. Nan Miao, Wenjie Cai, Sijia Ding, Yajuan Liu, Wanhua Chen and Tao Sun (#) (2022). Characterization of plasma exosomal microRNAs in responding to radiotherapy of human esophageal squamous cell carcinoma. Molecular Medicine Reports. 2022 Sep;26(3):287. doi: 10.3892/mmr.2022.12803.

  7. Nan Miao, Xiaodong Lai, Zhiwei Zeng, Wenjie Cai, Wanhua Chen and Tao Sun (#)(2020). Differential expression of microRNAs in the human fetal left and right cerebral cortex. Molecular Biology Reports. 47(9):6573-6586. doi: 10.1007/s11033-020-05708-9. 

  8. Nan Miao; Shan Bian, Trevor Lee, Taufif Mubarak, Shiying Huang, Zhihong Wen, Ghulam Hussain and Tao Sun (#) (2018). Opposite Roles of Wnt7a and Sfrp1 in Modulating Proper Development of Neural Progenitors in the Mouse Cerebral Cortex. Frontiers in Molecular Neuroscience. 11:247. doi: 10.3389/ fnmol. 2018. 00247 

  9. Nan Miao, Jun ghee Jin, Seung-Nam Kim and Tao Sun#(2018); Hippocampal MicroRNAs Respond to Administration of Antidepressant Fluoxetine in Adult Mice. International Journal of Molecular Sciences. 2018, 19(3), 671; https://doi.org/10.3390/ijms19030671

  10. Nan Miao, Xin Wang, Yanping Feng# and Yanzhang Gong# (2017). Male-biased miR-92 from early chicken embryonic gonads directly targets ATRX and DDX3X. Gene. 2017 Aug 30; 626:326-336. doi: 10.1016/j.gene.2017.05.050. 

  11. Nan Miao, Xin Wang, Yue Hou, Yanping Feng# and Yanzhang Gong# (2016). Identification of male-biased microRNA-107 as a direct regulator for nuclear receptor subfamily 5 group A member 1 based on sexually dimorphic microRNA expression profiling from chicken embryonic gonads. Molecular and Cellular Endocrinology. doi:10.1016/j.mce.2016.03.033

(2)参与作者

1.Chen Y, Ye W, Wang W, Miao N, Sha Y, Sun T. Nicotinic acid (NA) facilitates antidepressant effects through promoting neuro-protective transcriptome in the hippocampus. Pharmacol Biochem Behav. 2026 Feb;259:174145. doi: 10.1016/j.pbb.2025.174145.

2. Xie H, Chen Y, Xu S, Miao N, Zheng W, Jiang C, Sun T. Increasing age in men is negatively associated with sperm quality and DNA integrity but not pregnancy outcomes in assisted reproductive technology. Front Aging. 2025 May 21;6:1603916. doi: 10.3389/fragi.2025.1603916

3. Jing Wang, Zixi Chen, Fei He, Trevor Lee, Wenjie Cai, Wanhua Chen, Longbin Zhang, Nan Miao, Zhiwei Zeng, Ghulam Hussain, Qiwei Guo, Tao Sun(#) (2022). Single-cell transcriptomics reveals diverse and complex gene expression alterations in human trisomy 18. Frontiers in Cell and Developmental Biology. doi: 10.3389/fcell.2022.825345. 

4. Yuanyuan Sun, Nan Miao and Tao Sun (#)(2019). Detect accessible chromatin using ATAC-sequencing, from principle to applications. Hereditas. 2019 Aug 15;156:29.  doi: 10.1186/s41065-019-0105-9. 

5. Zhiwei Zeng, Nan Miao and Tao Sun(#)(2018). Revealing cellular and molecular complexity of the central nervous system using single cell sequencing. Stem cell Research & Therapy

6. Jennifer L. Knauss, Nan Miao, Seung-Nam Kim, Yanzhen Nie, Yuelin Shi, Tao Wu, Hugo Borges Pinto, Mary E. Donohoe and Tao Sun (#) (2018). Long noncoding RNA Sox2ot and transcription factor YY1 co-regulate the differentiation of cortical neural progenitors by repressing Sox2. Cell Death & Disease. 9:799, doi: 10.1038/s41419-018-0840-2. 

(3)专利:

1. MIAO Nan;PAN Xian;SUN Tao. Animal model of neural-specific PIWIL1 gene knockout mice, construction method and application thereof. F/PT/NC/O/2026/21030 (授权)

2. MIAO NanPAN Xian;SUN Tao. Animal model of neural-specific 9130024F11Rik gene knockout mice, construction method and application thereofF/PT/NC/O/2026/21027 (授权)

3. 苗楠,潘贤,孙涛,神经特异性敲除PIWIL1基因突变小鼠动物模型及其构建方法、应用,2023-12-06,申请号:202311663558.3。

4. 苗楠,潘贤,孙涛,神经特异性敲除9130024F11Rik基因突变小鼠动物模型及其构建方法、应用2023-12-06,申请号:202311664519.5


5. 本科生培养:

(1)毕业设计

21级 黄越   刘盼盼(宁夏医科大学)

20级  樊志乔  杨勇杰   潘金强

19级  郝佳宝 优秀毕业论文,中山大学研究生 蒋宇程   洪少阳

18级  张雪宁 (优秀毕业论文,浙江大学研究生)  朱可滢(南京医科大学研究生) 杨夕宇

17级  邵业

16级  方敏 (优秀毕业论文,曼彻斯特大学研究生) 张瑞豪   刘秋阳 (优秀毕业论文,四川大学研究生)

(2)成长导师

21级临床专业    戴    旺(国家励志奖学金,医学技能大赛三等奖)    张   琪

22级临床专业    吴炜斌    吴恒煊

24级临床专业    彭国栋

Educational Experience

  • 2010.9 -- 2016.6

    华中农业大学       Animal Genetic Breeding and Reproduction       With Certificate of Graduation for Doctorate Study       Doctoral degree

  • 2006.9 -- 2010.6

    华中农业大学       大学本科       Bachelor's degree

  • 2006.9 -- 2010.6

    武汉大学       Developmental Biology       大学本科       Double Degree

Work Experience

  • 2023.12 -- Now

    华侨大学医学院      精准分子医疗中心-孙涛课题组      第五党支部书记      副教授      在职

  • 2016.9 -- 2023.12

    华侨大学医学院      精准分子医疗中心-孙涛课题组      第五党支部书记      讲师      在职

Awards and Honours

Paper Publications

Social Affiliations

  • Nutrient 审稿人

  • International Journal of Molecular Sciences审稿人

  • Aging审稿人

  • Journal of Clinical Medicine审稿人

  • Frontiers in Neuroscience审稿人

  • Molecular and Cellular Biochemistry审稿人

  • Journal of Personalized Medicine审稿人

  • Brain Sciences审稿人

  • BIOCELL审稿人

Teaching Information